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Question: Marijuana (THC) is an extremely powerful and pleasurable intoxicant. Its affects alter and damage brain cells that control thinking, Damage? The harmful effects of marijuana on the Endocrine System Marijuana damages the network of glands, organs, and hormones involved in growth and development, energy levels, and reproduction. Doesn't this argue for legalization and regulation of cannabis, so people with heart or BP trouble can read the labels and decide for themselves if they're up to the risk?
Answer: An increase in seratonin means it increases synaptic activity, (I can use this as evidence to the "person" who called my claim of grass as a stimulant "a crock of redneck drug-knowledge ") but where? In all the brain? No. The receptors that have a high binding density (which means that the cannabinoids will bind more there than elsewhere) are in the cerebellum and the basal ganglia, which are parts of the brain that are associated with movement and the perception of time, the hippocampus, which plays a role in memory, and the cortex, which is responsible for perception and reasoning. As an aside I will mention that the brain stem, which controls most life functions like heart, lungs etc, have a very low binding density, which is why no one has died from ingestion of grass in any form as of yet. Seratonin affects your mood, therefore the feeling of euphoria. Many neurotransmitters have a dual purpose and we can know this by looking at the parts of the brain that are affected by grass. We can reason that the increased synaptic in the affected areas of the brain is the reason for the sensations that one feels while under the influence of grass. An increase in synaptic in the basal ganglia affects our perception of time because more synapses are firing in a set period of time while "high" than as are when we are un-cannabinoid influenced. An infant, when learning to control his arms and his legs, is triggering a pathway of synapses over and over until it is hardwired. This is a learned route for each muscle into his brain, not a random triggering here and there. If the infant had to use a different pathway all the time he would never learn to bring his pacifier to his mouth by the age of 4 months. I use the Infant analogy because it parallels the case of the quadriplegic learning to use his muscles all over again by building a new pathway around the damaged section of the spinal chord.
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